Cadence Raises $100M, Adds Duke and Texas Health Resources

Cadence, a clinical AI company built around chronic disease management, has raised $100 million in a Series C round and signed new partnerships with Duke Health and Texas Health Resources, according to Becker's Hospital Review. The round was led by Spark Capital with participation from Thrive Capital, General Catalyst and Coatue.

Cadence pairs remote monitoring with clinical staff to manage patients with conditions like hypertension, diabetes and heart failure between visits. The model lets health systems extend care to chronically ill patients without adding their own headcount, a growing priority as systems face thin margins and clinician shortages.

The Duke and Texas Health Resources deals signal continued appetite among large systems for outside AI partners to handle high-volume, high-cost chronic care. For Cadence, landing marquee academic and regional health systems strengthens its case as investors keep pouring money into clinical AI aimed at measurable cost and outcome improvements rather than back-office tasks.